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標(biāo)記一抗
英文名稱Anti-ALS2CR3/FITC
中文名稱:FITC標(biāo)記的肌萎縮側(cè)索硬化癥相關(guān)蛋白3抗體
別 名ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.
規(guī)格:100ul
說 明 書100ul
研究領(lǐng)域細(xì)胞生物 神經(jīng)生物學(xué) Alzheimer's
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量101kDa
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亞 型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.
Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner
Tissue Specificity:
Widely expressed, with highest expression in heart.
Post-translational modifications:
O-glycosylated
Similarity:
Contains 1 HAP1 N-terminal domain.
Database links:
UniProtKB/Swiss-Prot: O60296.2
中文名稱:FITC標(biāo)記的肌萎縮側(cè)索硬化癥相關(guān)蛋白3抗體
別 名ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.
詳細(xì)介紹：
規(guī)格:100ul
說 明 書100ul
研究領(lǐng)域細(xì)胞生物 神經(jīng)生物學(xué) Alzheimer's
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量101kDa
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亞 型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資料：
產(chǎn)品介紹background:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.
Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner
Tissue Specificity:
Widely expressed, with highest expression in heart.
Post-translational modifications:
O-glycosylated
Similarity:
Contains 1 HAP1 N-terminal domain.
Database links:
UniProtKB/Swiss-Prot: O60296.2
